Methods: Forty SD rats were randomly divided into five groups: control group, model group and three DWN-treated groups.

方法：40只SD大鼠随机分为正常对照组、模型组和胆胃宁低、中、高剂量组共5组。

DWN potently inhibited both decrease of SOD and PGE2 and increase of MDA in damaged gastric mucosa induced by ethanol in a dose-dependent manner.

胆胃宁尚可有效抑制乙醇损伤胃黏膜所致的SOD和PGE2降低以及MDA升高，且具有剂量依赖性。

Objective: To study the protective effect and the mechanism of Chinese herbal medicine Dan-Wei-Ning(DWN) on alcohol-induced gastric mucosal damage.

目的：研究中药胆胃宁对无水乙醇所致胃黏膜损伤的保护作用及作用机制。

Results: DWN could lessen gastric mucous injury, inhibit ulcerous formation and improve pathological changes of damaged gastric mucosa induced by alcohol.

结果：胆胃宁能减轻乙醇所致胃黏膜损伤，抑制溃疡形成，改善胃黏膜组织学损害。