Inhibition rate of each group and the PARP activity of changes.

观察各组细胞抑制率和PARP活性改变。

But a new category of drug called PARP inhibitors may change that.

然而一种名叫PARP抑制剂的药物可能会改变现状。

PARP inhibition may prove beneficial for the treatment of atherosclerosis.

PARP抑制可能会被证实对动脉粥样硬化的治疗有帮助。

Trapped PARP-DNA complexes have been shown to be cytotoxic to cancer cells.

捕获PARP - DNA复合物已被证明对肿瘤细胞具有毒性。

The first is that PARP-1, a protein found in every cell, becomes activated whenever a cell's DNA is damaged.

第一是观察到PARP - 1存在于每个细胞中，并且当细胞DNA受损伤时能激活该蛋白质。

To estimate the relative risk and the population attributable risk percent (PARP) of main risk factors by comprehensive analysis.

利用综合分析方法估计我国人群三种肿瘤的主要危险因素的相对危险度及人群归因危险度百分比。

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the caspase cleavage site in PARP.

该多克隆抗体是采用合成的PARP裂解位点周围残基相对应的肽段免疫动物后制备获得。

When DNA damages of cells appear, as a kind of molecular sensor of cells, PARP will recognize and bind to DNA breakages, then be activated.

当细胞DNA发生损伤时，PARP可作为细胞内的分子感受器，识别、结合到DNA断裂处，并被激活。

The study authors conclude that it is very likely that minocycline's neuroprotective and anti-inflammatory effects are due to PARP-1 inhibition.

文章的作者总结道，二甲胺四环素的神经保护和抗炎作用很可能是由于抑制了PARP-1。

"Minocycline turns out to be an extraordinarily good PARP inhibitor, better than most of the drugs that are marketed as PARP inhibitors," he says.

Swanson博士说：“二甲胺四环素是一种极其有效的PARP抑制剂，比市场上标明PARP抑制剂的药物更有用。”

The researchers then tested a number of different drugs on the cells, discovering that they were killed by drugs belonging to a group known as PARP inhibitors.

然后，研究人员在细胞上测试了许多不同的药物，发现它们被称为属于PARP抑制剂种类的药物杀死。

This occurred in tumors that were PARP inhibitor-resistant from the start as well as those that initially responded to PARP inhibitors but became resistant later on.

这种情况出现在开始就对PARP抑制剂耐药以及起初对PARP抑制剂有治疗反应，但后来耐药的肿瘤中。

The cleavage of Poly(ADP ribose)polymerase(PARP) is an molecular event of the activation of cysteine protease, and it is also an early molecular marker of apoptosis .

的蛋白酶解为半胱氨酸蛋白酶激活的分子事件，是细胞程序死亡的一个早期分子标志。

Objective: To observe the expression of poly (ADP-ribose) polymerase (PARP) in focal cerebral ischemia with reperfusion injury and explore the role of PARP in apoptosis.

目的观察多聚ADP 核糖聚合酶（PARP）在脑缺血再灌流损伤中的表达，探讨PARP在细胞凋亡中的作用。

The on-going technologies on reducing OFDM signal PARP can be generally divided into three categories: limiting class technologies, encoding techniques and signal scrambler technologies.

目前降低OFDM信号PAR的技术总体上可分为三类：信号畸变技术、概率类技术和信号编码类技术。

We hypothesized that PARP may play an important role in atherogenesis and that its inhibition may attenuate atherosclerotic plaque development in an experimental model of atherosclerosis.

我们假设PARP可能在动脉粥样硬化形成中起重要作用，它的抑制可能会减弱动脉粥样硬化实验模型中动脉硬化斑块的进展。

It has been proved that PARP has lots of physiological and biochemistry functions and correlates with cell death. Many kinds of damage factors such as radiation may influence the activity of PARP.

已经证实，PARP具有多种生理、生化功能，并与细胞的死亡相关，电离辐射等各种细胞损伤因素都可以影响parp活性。