A little effort every day, you will make a big difference.

每天付出一点努力，你就会有很大的不同。

When it comes to climate change, can they make a big difference?

在气候变化问题上，他们能起到很大的作用吗？

She believed that such an experience would make a big difference to her 9-year-old boy's life.

她相信这样的一次经历会给9岁孩子的人生带来很大的改变。

Your choice of words can make a big difference, too.

你的用词也会产生很大的影响。

Inventions usually make a big difference to people's lives.

发明通常对人们的生活有很大的影响。

For small mammals, microclimates can make a big difference.

对于小型哺乳动物来说，微气候可以产生很大的影响。

This little bit of support can sometimes make a big difference.

这种小小的支持有时会产生很大的影响。

Even a few hours a month can make a big difference in someone's life.

即使是一个月几个小时，也会对一个人的生活产生很大的影响。

Researchers at Duke University scrutinized more than 160 published studies and found an absence of strong evidence that any of these approaches can make a big difference.

杜克大学的研究人员详细核查了160多项已发表的研究，发现并没有强有力的证据表明这些方法中的任意之一能产生重大作用。

That would make a big difference.

那就将使情况大为改观了。

This can make a big difference to local prices.

这可以使它获得与当地的悬殊价差。

Even relatively mild stresses make a big difference.

即使相对柔和的压力也会带来很大改变。

This small change in your mindset can make a big difference.

头脑中这一点小小的变化将会很大改变。

A few years can make a big difference in the life of a nation.

在一个民族的历史长河中，短短几年的时间就有可能被改变一切。

I'm sure it would make a big difference to our learning ability.

我相信这一改变能够大大提高我们的学习能力。

'Transparency is going to make a big difference,' the aide said.

这位助手说，透明将带来很大的转变。

But I am confident that improving diet can make a big difference.

但是我坚信着改善饮食习惯是可以改变这种状况的。

Is it a goal that will really make a big difference in your life?

有没有什么目标会真正的让你的生活不一样的呢？

A few simple tips can make a big difference to your frame of mind.

一些简单的窍门就会给你的心情带来大大的改变。

The trust factor of friends' Suggestions can make a big difference. Mr.

朋友建议中的信任因素则可能令结果完全不同。

The trust factor of friends’ suggestions can make a big difference.

朋友建议中的信任因素则可能令结果完全不同。

But whether or not you do so doesn't seem to make a big difference.

但不论你是否选择这样做，都不会有什么太大的影响？

Marketing can also make a big difference to a company's performance.

市场营销对公司的表现来说也是至关重要。

Researchers say there's a reason why even 30 minutes can make a big difference.

研究者说之所以仅30分钟就造成很大差别是有原因的。

That one little change can make a big difference in the overall look of your shot.

这一点小小的改变会给照片的整体效果带来非常大的改变。

Breast-feeding advice, food supplements and better hygiene all make a big difference.

母乳喂养指导、食物进补以及更好的保健都会产生显著变化。

For such smaller Banks, even modest inflows of new deposits can make a big difference.

对于这些小银行来说，即使小的新的资金流入也能够产生大的作用。